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Atomoxetine General Info


Atomoxetine pills General Info

The exact mechanism by which Atomoxetine medication has a therapeutic effect in attention deficit hyperactivity disorder (ADHD) is unknown, but it is believed to be associated with selective inhibition of the presynaptic noradrenaline transporter (determined in vitro studies) throughout the brain. There is evidence of inhibition of dopamine reuptake in the prefrontal cortex, where expression of the dopamine transporter (DAT) is minimal. Atomoxetine does not belong to psychostimulants and is not a derivative of amphetamine. 
The drug of new generation contributes to blocking the reuptake of norepinephrine. This action is carried out directly through the interaction of proteins. It also helps to increase the concentration of norepinephrine in the synaptic cleft and enhance direct synaptic transmissions. 
The goal of treatment with Atomoxetine pill is to improve attention, reduce motor hyperactivity and impulsivity that interfere with social functioning. Treatment must be continued until the result is achieved. If necessary, it is necessary to periodically resume treatment.
Expected Result The effect of treating ADHD is visible on the first day; Improvement effect lasts for 8-12 weeks; If after 6-8 weeks there is no Atomoxetine effect, it is necessary to refuse from taking this drug.
Contraindications: Simultaneous use with MAO inhibitors. Closed angle glaucoma. Hypersensitivity to the drug. The drug must be taken with caution if the patient is suffering from: Hypertension. Tachycardia Cardiovascular diseases or disorders of cerebral circulation. –°onditions that can lead to hypotension.
The usage during pregnancy and lactation. 
Clinical experience with atomoxetine during pregnancy is insufficient, so the drug should be prescribed during pregnancy only if the expected benefit of therapy for the mother far exceeds the potential risk to the fetus. It is not known whether atomoxetine is secreted in breast milk. If necessary, the appointment of the drug in this group of patients requires caution.

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Article is posted by Helen Molina, MD

You can get more info here: Atomoxetine on Wikipedia