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Coumadin General Info


Coumadin pills General Info

Coumadin is an anticoagulant of indirect action. Coumadin is produced in the form of tablets, 5, 10, 14, 20, 25 pieces in blisters, or 50, 100, 250 pieces in cans. The composition of 1 tablet contains the active substance - warfarin sodium in the amount of 2.5 mg.
Laboratory studies, which were using a radioactive label, have demonstrated that, after a single oral dose, approximately 92% of warfarin is eliminated through the kidneys as metabolites and only a small amount unchanged. 
Coumadin is prescribed for the treatment and prevention of thrombosis and embolism of blood vessels. 
Indications for use are the following diseases: 
Pulmonary embolism and acute venous thrombosis; 
Repeated pulmonary embolism;
Repeated myocardial infarction; 
Postoperative or repetitive venous thrombosis; 
Prosthetic heart valves and veins (perhaps in the mix with acetylsalicylic corrosive); 
Thrombosis of the cerebral, coronary and fringe supply routes; 
Coumadin is additionally utilized as an extra in the therapeutic or careful treatment of thrombosis and in electrical cardioversion of atrial fibrillation.
Instructions for use of Coumadin 
Tablets should be ingested 2-10 mg per day. The daily dosage is determined by the parameters of blood coagulation, the patient's response to treatment, and the clinical situation. 
Side effects of Coumadin
When using Coumadin, you may develop disorders of the various systems and organs: 
Digestive system: cholestasis, nausea, hepatitis, diarrhea, vomiting, increased activity of liver enzymes, abdominal pain, jaundice; 
Blood coagulation system: hematomas, bleeding, anemia; rarely, necrosis of the skin and other tissues due to local thrombosis; 
Central nervous system: a headache, lethargy, fatigue, asthenia, taste disturbances, dizziness; 
Cardiovascular system: vasculitis, purple staining of toes, chills, feeling cold, paresthesia.

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Article is posted by Helen Molina, MD

You can get more info here: Coumadin on Wikipedia