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Acetaminophen General Info


Acetaminophen pills General Info

Acetaminophen is a drug that has analgesic, antipyretic and anti-inflammatory effects.
The active ingredient of Acetaminophen is paracetamol, an analgesic-antipyretic that has analgesic, antipyretic and weak anti-inflammatory effects. The mechanism of its work is associated with a decrease in the excitability of the hypothalamus thermoregulation center.
After a patient uses it in an oral way, paracetamol is rapidly absorbed from the gastrointestinal tract, mainly in the small intestine. As a result of a single dose of 500 mg of paracetamol, its maximum concentration in the blood plasma is reached after 10–60 minutes. The substance is widely distributed mainly in body fluids, with the exception of cerebrospinal fluid, and in tissues, with the exception of lipid tissue.
Acetaminophen, instructions for use: method and dosage of this tablets should be at a dose of 500 mg 3-4 times a day. It is not recommended to exceed the maximum daily dose of 4 g and continue taking the drug for more than 5-7 days.
The use of Acetaminophen can cause the following side effects:
Dyspepsia from the gastrointestinal tract;
Thrombocytopenia;
Agranulocytosis;
Leukopenia;
Neutropenia;
Pancytopenia;
Overdose Symptoms of paracetamol in the first 24 hours are nausea, vomiting, pallor, pain in the abdominal region. After 12–48 hours, dysfunction of the kidneys and liver with the development of liver failure (up to encephalopathy, coma, death), as well as there are situations where pancreatitis and cardiac arrhythmias are possible. It is possible for adults to get a live damage when they take doses of 10 g or more.

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Article is posted by Helen Molina, MD

You can get more info here: Acetaminophen on Wikipedia